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Long-term ventilation of patients with Duchenne muscular dystrophy: experiences at the Neuromuscular Centre Ulm

2020-07-16T10:00:28+02:00

The various measures used to treat the symptoms of Duchenne muscular dystrophy (DMD), i.e. medication with steroids, early operation on contractures and spine deformities as well as cardiac diagnostics and therapy, should always be accompanied by careful monitoring of the patient's respiratory status. Therapy for respiratory failure, in particular long-term ventilation, is now [...]

Long-term ventilation of patients with Duchenne muscular dystrophy: experiences at the Neuromuscular Centre Ulm2020-07-16T10:00:28+02:00

Effectiveness of Cough Assist Device in Exercise Capacity in COPD Patients

2020-07-20T10:58:30+02:00

Coughing is the body’s defense mechanism to clear the airways from the foreign bodies and secretions. In patients with neuromuscular disorders or other diseases affecting the airways such as cystic fibrosis (CF), the effectiveness of this defense mechanism is often reduced due to respiratory exhaustion. Some COPD patients have also difficulty in airway [...]

Effectiveness of Cough Assist Device in Exercise Capacity in COPD Patients2020-07-20T10:58:30+02:00

2020-07-15T11:30:32+02:00

Many neurological diseases may cause acute respiratory failure (ARF) due to involvement of bulbar respiratory center, spinal cord, motoneurons, peripheral nerves, neuromuscular junction, or skeletal muscles. In this context, respiratory emergencies are often a challenge at home, in a neurology ward, or even in an intensive care unit, influencing morbidity and [...]

2020-07-15T11:30:32+02:00

Intrapulmonary percussive ventilation leading to 20-minutes breath-hold potentially useful for radiation treatments

2020-07-15T10:50:08+02:00

We developed a training protocol based on Intrapulmonary Percussive Ventilation in order to prolong breath-hold while nearly suppressing the thorax motion. This protocol allowed ten subjects to achieve a 20-minutes-breath-hold, while reducing the residual surface motion to 1 mm around its mean position for more than 95% of the breath-hold duration. Keywords: Breath-hold; Cancer; [...]

Intrapulmonary percussive ventilation leading to 20-minutes breath-hold potentially useful for radiation treatments2020-07-15T10:50:08+02:00

“Hospital at home” for neuromuscular disease patients with respiratory tract infection: a pilot study

2020-07-15T10:36:23+02:00

Background: The "hospital-at-home" model may provide adequate care without an adverse effect on clinical outcome, and is generally well received by users. Our objective was to compare hospital-at-home and in-patient hospital care for neuromuscular disease (NMD) patients with respiratory tract infections. Methods: We conducted a prospective randomized controlled trial in a university teaching hospital offering [...]

“Hospital at home” for neuromuscular disease patients with respiratory tract infection: a pilot study2020-07-15T10:36:23+02:00

Prevention of extubation failure in high-risk patients with neuromuscular disease

2020-07-15T10:29:57+02:00

Background: A substantial proportion of patients with neuromuscular disease (NMD) who undergo positive pressure ventilation via endotracheal intubation for acute respiratory failure fail to pass spontaneous breathing trials and should be considered at high risk for extubation failure. In our study, we prospectively investigated the efficacy of early application of noninvasive ventilation (NIV) combined [...]

Prevention of extubation failure in high-risk patients with neuromuscular disease2020-07-15T10:29:57+02:00
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